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1

Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product P16 INK4A in ovarian cancer is associated with progression and unfavourable prognosis

Ying Dong, Michael D. Walsh, Michael A. McGuckin, Brian B. Gabrielli, Margaret C. Cummings, R. Gordon Wright, Terry Hurst, Soo Keat Khoo, Peter G. Parsons

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 336 KB

english, 1997

2

Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer

Ying Dong, Michael D. Walsh, Michael A. McGuckin, Margaret C. Cummings, Brian G. Gabrielli, Gordon R. Wright, Terry Hurst, Soo Keat Khoo, Peter G. Parsons

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 347 KB

english, 1997

3

Functional reassessment of P16 variants using a transfection-based assay

Graeme J. Walker, Brian G. Gabrielli, Marina Castellano, Nicholas K. Hayward

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 432 KB

english, 1999

4

Restoration of CDKN2A into Melanoma Cells Induces Morphologic Changes and Reduction in Growth Rate but Not Anchorage-Independent Growth Reversal.

Castellano, Marina, Gabrielli, Brian G., Hussussian, Christopher J., Dracopoli, Nicholas C., Hayward, Nicholas K.

Journal:

The Journal of Investigative Dermatology

Year:

1997

File:

PDF, 3.33 MB

1997

5

10.1038/3882

Khanna, Kum Kum, Keating, Katherine E., Kozlov, Sergei, Scott, Shaun, Gatei, Magtouf, Hobson, Karen, Taya, Yoichi, Gabrielli, Brian, Chan, Doug, Lees-Miller, Susan P., Lavin, Martin F.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

6

Regulation of CDC25B phosphatases subcellular localization

Davezac, Noélie, Baldin, Véronique, Gabrielli, Brian, Forrest, Alistair, Theis-Febvre, Nathalie, Yashida, Minoru, Ducommun, Bernard

Journal:

Year:

2000

Language:

english

File:

PDF, 244 KB

english, 2000

7

Cdc25B activity is regulated by 14-3-3

Forrest, Alistair, Gabrielli, Brian

Journal:

Year:

2001

Language:

english

File:

PDF, 314 KB

english, 2001

8

G2 phase cell cycle arrest in human skin following UV irradiation

Pavey, Sandra, Russell, Terry, Gabrielli, Brian

Journal:

Year:

2001

Language:

english

File:

PDF, 457 KB

english, 2001

9

The EBNA- 3 gene family proteins disrupt the G2/M checkpoint

Krauer, Kenia G, Burgess, Andrew, Buck, Marion, Flanagan, James, Sculley, Tom B, Gabrielli, Brian

Journal:

Year:

2003

Language:

english

File:

PDF, 444 KB

english, 2003

10

Histone deacetylase inhibitors specifically kill nonproliferating tumour cells

Burgess, Andrew, Ruefli, Astrid, Beamish, Heather, Warrener, Robyn, Saunders, Nicholas, Johnstone, Ricky, Gabrielli, Brian

Journal:

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

11

Defining the Chemotherapeutic Targets of Histone Deacetylase Inhibitors

BRIAN GABRIELLI, ROBYN WARRENER, ANDREW BURGESS, HEATHER BEAMISH

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

12

CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity

Rose Boutros, Corinne Lorenzo, Odile Mondesert, Alain Jauneau, Vanessa Oakes, Christine Dozier, Brian Gabrielli, Bernard Ducommun

Journal:

Biology of the Cell

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

13

Centrosomal and Cytoplasmic Cdc2/Cyclin B1 Activation Precedes Nuclear Mitotic Events

Colin P.C. De Souza, Kay A.O. Ellem, Brian G. Gabrielli

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 273 KB

english, 2000

14

Phosphorylation of ribosomal protein S6 and a peptide analogue of S6 by a protease-activated kinase isolated from rat liver

Brian Gabrielli, Richard E.H. Wettenhall, Bruce E. Kemp, Michael Quinn, Lily Bizonova

Journal:

Year:

1984

Language:

english

File:

PDF, 1.78 MB

english, 1984

15

Cdk1/Erk2- and Plk1-Dependent Phosphorylation of a Centrosome Protein, Cep55, Is Required for Its Recruitment to Midbody and Cytokinesis

Megan Fabbro, Bin-Bing Zhou, Mikiko Takahashi, Boris Sarcevic, Preeti Lal, Mark E. Graham, Brian G. Gabrielli, Phillip J. Robinson, Erich A. Nigg, Yoshitaka Ono, Kum Kum Khanna

Journal:

Developmental Cell

Year:

2005

Language:

english

File:

PDF, 873 KB

english, 2005

16

Histone deacetylase inhibitors in the generation of the anti-tumour immune response

Leggatt, Graham R, Gabrielli, Brian

Journal:

Immunology & Cell Biology

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

17

Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells

Pike, Tanya, Widberg, Charlotte, Goodall, Andrew, Payne, Elizabeth, Giles, Nichole, Hancock, John, Gabrielli, Brian

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 526 KB

english, 2013

18

Activation of p34cdc2Kinase by Cyclin A

Linda M. Roy, Katherine I. Swenson, Duncan H. Walker, Brian G. Gabrielli, Run Sheng Li, Helen Piwnica-Worms and James L. Maller

Journal:

The Journal of Cell Biology

Year:

1991

Language:

english

File:

PDF, 2.01 MB

english, 1991

19

Decatenation checkpoint-defective melanomas are dependent on PI3K for survival

Brooks, Kelly, Ranall, Max, Spoerri, Loredana, Stevenson, Alex, Gunasingh, Gency, Pavey, Sandra, Meunier, Fred, Gonda, Thomas J., Gabrielli, Brian

Journal:

Pigment Cell & Melanoma Research

Year:

2014

Language:

english

File:

PDF, 7.65 MB

english, 2014

20

Similar, not the same

Spoerri, Loredana, Gabrielli, Brian

Journal:

Year:

2013

Language:

english

File:

PDF, 247 KB

english, 2013

21

Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle

Oakes, Vanessa, Wang, Weili, Harrington, Brittney, Lee, Won Jae, Beamish, Heather, Chia, Kee Ming, Pinder, Alex, Goto, Hidemasa, Inagaki, Masaki, Pavey, Sandra, Gabrielli, Brian

Journal:

Year:

2014

Language:

english

File:

PDF, 897 KB

english, 2014

22

Histone-Deacetylase Inhibitors for the Treatment of Cancer

Lindemann, Ralph K., Gabrielli, Brian, Johnstone, Ricky W.

Journal:

Year:

2004

Language:

english

File:

PDF, 459 KB

english, 2004

23

Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity

Astuti, Puji, Gabrielli, Brian

Journal:

Year:

2011

Language:

english

File:

PDF, 1.89 MB

english, 2011

24

High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene

Ranall, Max, Gabrielli, Brian, Gonda, Thomas

Journal:

Year:

2011

Language:

english

File:

PDF, 2.42 MB

english, 2011

25

DCT protects human melanocytic cells from UVR and ROS damage and increases cell viability

Ainger, Stephen A., Yong, Xuan L., Wong, Shu S., Skalamera, Dubravka, Gabrielli, Brian, Leonard, J. Helen, Sturm, Richard A.

Journal:

Experimental Dermatology

Year:

2014

Language:

english

File:

PDF, 510 KB

english, 2014

26

A UVR-Induced G2-Phase Checkpoint Response to ssDNA Gaps Produced by Replication Fork Bypass of Unrepaired Lesions Is Defective in Melanoma

Wigan, Matthew, Pinder, Alex, Giles, Nichole, Pavey, Sandra, Burgess, Andrew, Wong, ShuShyan, Sturm, Rick A, Gabrielli, Brian

Journal:

The Journal of Investigative Dermatology

Year:

2012

Language:

english

File:

PDF, 5.74 MB

english, 2012

27

Phenotypic Characterization of Nevus and Tumor Patterns in MITF E318K Mutation Carrier Melanoma Patients

Sturm, Richard A, Fox, Carly, McClenahan, Phil, Jagirdar, Kasturee, Ibarrola-Villava, Maider, Banan, Parastoo, Abbott, Nicola C, Ribas, Gloria, Gabrielli, Brian, Duffy, David L, Soyer, H Peter

Journal:

The Journal of Investigative Dermatology

Year:

2014

Language:

english

File:

PDF, 2.11 MB

english, 2014

28

Defective Decatenation Checkpoint Function Is a Common Feature of Melanoma

Brooks, Kelly, Chia, Kee Ming, Spoerri, Loredana, Mukhopadhyay, Pamela, Wigan, Matthew, Stark, Mitchell, Pavey, Sandra, Gabrielli, Brian

Journal:

The Journal of Investigative Dermatology

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014

29

Keeping replicative stress in Chk

Brooks, Kelly, Gabrielli, Brian

Journal:

Year:

2012

Language:

english

File:

PDF, 507 KB

english, 2012

30

JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase

Pinder, Alex, Loo, Dorothy, Harrington, Brittney, Oakes, Vanessa, Hill, Michelle M., Gabrielli, Brian

Journal:

Cellular Signalling

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

31

Finally, how histone deacetylase inhibitors disrupt mitosis!

Gabrielli, Brian, Chia, KeeMing, Warrener, Robyn

Journal:

Year:

2011

Language:

english

File:

PDF, 835 KB

english, 2011

32

Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells

Beaumont, Kimberley A., Hill, David S., Daignault, Sheena M., Lui, Goldie Y.L., Sharp, Danae M., Gabrielli, Brian, Weninger, Wolfgang, Haass, Nikolas K.

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

33

Self-Renewal and High Proliferative Colony Forming Capacity of Late-Outgrowth Endothelial Progenitors Is Regulated by Cyclin-Dependent Kinase Inhibitors Driven by Notch Signaling

Patel, Jatin, Wong, Ho Yi, Wang, Weili, Alexis, Josue, Shafiee, Abbas, Stevenson, Alexander J., Gabrielli, Brian, Fisk, Nicholas M., Khosrotehrani, Kiarash

Journal:

Year:

2016

Language:

english

File:

PDF, 910 KB

english, 2016

34

A distinct expression profile separates Turkish and Australian melanocytic naevi

Fox, Carly, Schaider, Helmut, Akalin, Taner, Turkmen, Meltem, Sturm, Rick, Lambie, Duncan, Karaarslan, Isil K, Soyer, H Peter, Ozdemir, Fezal, Gabrielli, Brian

Journal:

Year:

2016

Language:

english

File:

PDF, 559 KB

english, 2016

35

A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma

Spoerri, Loredana, Brooks, Kelly, Chia, KeeMing, Grossman, Gavriel, Ellis, Jonathan J., Dahmer-Heath, Mareike, Škalamera, Dubravka, Pavey, Sandra, Burmeister, Bryan, Gabrielli, Brian

Journal:

Pigment Cell & Melanoma Research

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

36

A mutation in the Cdon gene potentiates congenital nevus development mediated by NRAS Q61K

Chitsazan, Arash, Ferguson, Blake, Ram, Ramesh, Mukhopadhyay, Pamela, Handoko, Herlina Y., Gabrielli, Brian, Soyer, Peter H, Morahan, Grant, Walker, Graeme J.

Journal:

Pigment Cell & Melanoma Research

Year:

2016

Language:

english

File:

PDF, 804 KB

english, 2016

37

Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma

Lee, Won Jae, Škalamera, Dubravka, Dahmer-Heath, Mareike, Shakhbazov, Konstanin, Ranall, Max V., Fox, Carly, Lambie, Duncan, Stevenson, Alexander J., Yaswen, Paul, Gonda, Thomas J., Gabrielli, Brian

Journal:

Journal of Biomolecular Screening

Year:

2016

Language:

english

File:

PDF, 5.01 MB

english, 2016

38

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities

Haass, Nikolas K., Gabrielli, Brian

Journal:

Experimental Dermatology

Year:

2017

Language:

english

File:

PDF, 286 KB

english, 2017

39

Inhibition of Aurora A and Aurora B is required for the sensitivity of HPV-driven cervical cancers to Aurora kinase inhibitors

Martin, David, Fallaha, Sora, Proctor, Martina, Stevenson, Alexander, Perrin, Lewis, McMillan, Nigel, Gabrielli, Brian

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

40

Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells

Levrier, Claire, Rockstroh, Anja, Gabrielli, Brian, Kavallaris, Maria, Lehman, Melanie, Davis, Rohan A., Sadowski, Martin C., Nelson, Colleen C.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.23 MB

english, 2017

41

Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS- Mutant Cancers

Hammerlindl, Heinz, Ravindran Menon, Dinoop, Hammerlindl, Sabrina, Emran, Abdullah Al, Torrano, Joachim, Sproesser, Katrin, Thakkar, Divya, Xiao, Min, Atkinson, Victoria G, Gabrielli, Brian, Haass, Ni

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 14.31 MB

english, 2017

42

Keratinocyte Sonic Hedgehog Up-regulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1 Secretion

Chitsazan, Arash, Ferguson, Blake, Villani, Rehan, Handoko, Herlina Y., Mukhopadhyay, Pamela, Gabrielli, Brian, Mooi, Wolter J., Soyer, H. Peter, Lambie, Duncan, Khosrotehrani, Kiarash, Morahan, Grant

Journal:

The Journal of Investigative Dermatology

Year:

2017

Language:

english

File:

PDF, 5.24 MB

english, 2017

43

Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

Stevenson, Alexander J., Ager, Eleanor I., Proctor, Martina A., Škalamera, Dubravka, Heaton, Andrew, Brown, David, Gabrielli, Brian G.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

44

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

Škalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian, Gonda, Thomas J., Jothi, Ra

Journal:

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

45

Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

Škalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J., Ray, Ranjit

Journal:

Year:

2012

Language:

english

File:

PDF, 2.97 MB

english, 2012

46

CDC25B Overexpression Stabilises Centrin 2 and Promotes the Formation of Excess Centriolar Foci

Boutros, Rose, Mondesert, Odile, Lorenzo, Corinne, Astuti, Puji, McArthur, Grant, Chircop, Megan, Ducommun, Bernard, Gabrielli, Brian, Fry, Andrew M.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.86 MB

english, 2013

47

Defective Cell Cycle Checkpoints as Targets for Anti-Cancer Therapies

Gabrielli, Brian, Brooks, Kelly, Pavey, Sandra

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.52 MB

english, 2012

48

Aurora kinases are a novel therapeutic target for HPV-positive head and neck cancers

Shaikh, Mushfiq H., Idris, Adi, Johnson, Newell W., Fallaha, Sora, Clarke, Daniel T.W., Martin, David, Morgan, Iain M., Gabrielli, Brian, McMillan, Nigel A.J.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

49

Pathway dysregulation analysis of the nucleotide excision repair mechanisms reveals it is not a common feature of melanomas

D'Arcy, Nicholas, Matigian, Nicholas, Lê Cao, Kim-Anh, Gabrielli, Brian

Journal:

Pigment Cell & Melanoma Research

Year:

2018

Language:

english

File:

PDF, 505 KB

english, 2018

50

Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening

Ranall, Max, Gabrielli, Brian, Gonda, Thomas

Journal:

Year:

2010

File:

PDF, 4.76 MB

2010